Pubblicato su stage4eu il: 19/09/2023 Novartis, Postgraduate Biologics Development, USP
Novartis Pharma
Forum 1, Basel, Svizzera
Chimica/Farmaceutica, Scienze naturali
12 mesi. Inizio: gennaio 2024
Attività:
- Support the development of efficient, high-yielding, robust and scalable fermentation processes for new biological entities
- Support the improvement and intensification of established fed-batch cell culture processes from vial break to harvest, including seed and main bioreactor stages
- Support the evaluation and implementation of new equipment and technologies (e.g. new feeding strategies) in the Upstream Process (USP) environment
- Design, plan, and execute USP lab activities, primarily parallel fermentation experiments, in our lab scale (<10 L) facility using state of the art disposable and glass bioreactor technology
- Work in multidisciplinary and international teams and at the interfaces to related drug substance process development and analytical functions.
Requisiti principali:
- Master of Science in Life Sciences, e.g., in Biotechnology, Biochemistry or Bioengineering with basic knowledge in upstream processing or equivalent education/experience
- Basic laboratory experience with mammalian cell cultures, primarily aseptic handling, ideally with shake flasks, wave and stirred bioreactors (experience in parallelized and automated cultivation in ambr250 systems is a plus)
- Intrinsic curiosity, willingness to adopt challenging tasks and grow in related areas of expertise (e.g. parallelized, automated cultivation)
- Experienced in independently planning, executing, and evaluating own laboratory experiments and presenting the data
- Proficiency in English, oral & written. Proficiency in German would be an additional asset.
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