Roche, Internship in BGE Reagents Development

In this internship, you will drive an exploratory feasibility project to evaluate novel oxygen scavenging strategies for next-generation blood gas reagent formulations. The project focuses on different innovative pathways such as small organic molecule scavengers, storage-stable enzymatic systems, and functional multilayer packaging foils.

Key responsibilities include:

• Organic Scavenger Screening & Electrochemistry: Identify and evaluate small organic molecules (e.g., food additives, antioxidants) to determine oxygen depletion kinetics while analyzing electrochemical behavior to minimize potential sensor interference.
• Enzymatic Scavenger Systems: Assess and validate enzyme-based systems for their feasibility and performance as effective oxygen scavengers.
• Functional Packaging & Materials Evaluation: Investigate active scavenging polymer laminates and pouch foils, conducting thorough leachables and extractables testing to safeguard sensor and reagent stability.
• Analytical Testing & Characterization: Apply advanced electrochemical, spectroscopic, and chromatographic methods to measure oxygen consumption rates and characterize matrix interactions.
• Data Analysis & Documentation: Synthesize experimental results, assess formulation and material viability, and present clear technical summaries and recommendations to the cross-functional R&D team.

• You are currently enrolled in, or have graduated from, a Master’s degree program (or equivalent advanced studies) in Chemistry, Organic Chemistry, Biochemistry, Chemical Engineering, Materials Science, or a related field within the last 12 months prior to your start date.
• You are eager to gain practical industry experience in a dynamic laboratory setting. Furthermore, You have:
• Strong theoretical and practical foundation in organic chemistry and wet-lab chemical formulation (Required).
• Sound knowledge of enzymes, enzyme kinetics, and biochemical reaction mechanisms (Required).
• High degree of self-organization, analytical problem-solving skills, and a structured approach to experimental design (Required).
• Excellent communication and teamwork abilities in English (Required).
• Interest or experience in electrochemistry (e.g., oxidation potentials, electrode interactions) or analytical techniques (e.g., UV/Vis spectrophotometry, fluorescence assays) (Preferred).
• Basic understanding of or curiosity about packaging materials, active foils, and leachables/extractables testing (Preferred).